HOXA11-AS

Across TCGA patient cohorts, HOXA11-AS RNA expression is significantly associated with the go_rna of many other GO terms, with 7,128 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible HOXA11-AS-associated GO terms across cancer lineages are Embryonic skeletal system development, Proximal/distal pattern formation, and Urogenital system development. Each is linked with HOXA11-AS in more than 18 cancer types. Because this analysis shows association rather than direction, both HOXA11-AS-to-partner and partner-to-HOXA11-AS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Embryonic skeletal system development grouped by HOXA11-AS-low versus HOXA11-AS-high in LAML.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXA11-AS→partner) and Y-score (partner→HOXA11-AS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LAML	Embryonic skeletal system development →	+0.043	+0.935	<.001	<.001	3	19
KICH	Proximal/distal pattern formation →	+0.081	+1.653	<.001	<.001	3	18
TGCT	Urogenital system development →	+0.050	+1.476	<.001	<.001	3	17
TGCT	Craniofacial suture morphogenesis →	+0.076	+1.325	<.001	<.001	3	17
TGCT	Embryonic forelimb morphogenesis →	+0.059	+1.521	<.001	<.001	3	17
ACC	Forelimb morphogenesis →	+0.043	+1.340	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,128 associations by consensus.

Embryonic skeletal system development by HOXA11-AS expression — LAML

Explore this box plot interactively →