HOXA10

Across TCGA patient cohorts, HOXA10 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,895 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible HOXA10-associated proteins across cancer lineages are SH3KBP1, MCM2, and MCM3. Each is linked with HOXA10 in more than 3 cancer types. Because this analysis shows association rather than direction, both HOXA10-to-partner and partner-to-HOXA10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HOXA10 versus SH3KBP1 in HNSC, with a Pearson correlation of -0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXA10→partner) and Y-score (partner→HOXA10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SH3KBP1 →	-0.420	-0.613	<.001	<.001	3	4
LUAD	MCM2 →	+0.490	+0.634	.004	.002	3	4
LUAD	MCM3 →	+0.511	+0.682	.004	.001	3	4
LUAD	MCM7 →	+0.505	+0.723	.003	<.001	3	4
LSCC	ARHGAP30 →	-0.447	-0.740	<.001	<.001	3	4
HNSC	XRCC1 →	+0.284	+0.770	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,895 associations by consensus.

HOXA10 vs SH3KBP1 — HNSC

Explore this scatter interactively →