Q-omics provides the consensus-scored HOXA10-AS profile across patient tissues and cancer cell-line models. HOXA10-AS expression is associated with patient survival in 19 of 34 cancer types, with the highest sampling consensus in CESC. Among the 18 cancer types available for tumor–normal comparison, HOXA10-AS is differentially expressed in 10, with the highest sampling consensus in HNSC. Additionally, HOXA10-AS RNA expression shows 13,994 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight CESC, HNSC, and TGCT as cancer lineages where HOXA10-AS shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for HOXA10-AS — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes HOXA10-AS survival associations across molecular data types. HOXA10-AS RNA expression shows survival associations in the most cancer types (19). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible HOXA10-AS RNA expression–survival associations across cancer types. High HOXA10-AS expression shows unfavorable associations in CESC, LGG, MESO, ACC and UCEC, but favorable associations in STAD. The CESC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify CESC as the clearest survival context for HOXA10-AS RNA expression.
This table summarizes HOXA10-AS tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 10. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for HOXA10-AS. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. HOXA10-AS shows higher tumor expression in HNSC, STAD, LUAD, UCEC, KIRP and LUSC. The HNSC box plot shows higher HOXA10-AS RNA expression in tumor versus normal tissue (log2 FC = +0.950, t-test p < 0.001).
This table shows molecular features associated with HOXA10-AS in patient tissues and cancer cell lines. In patient samples, HOXA10-AS shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set.
