HOXA-AS2

Across TCGA patient cohorts, HOXA-AS2 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,085 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible HOXA-AS2-associated proteins across cancer lineages are HOXA3_S184, HOXA4_S109, and HOXA3_S263. Each is linked with HOXA-AS2 in more than 6 cancer types. Because this analysis shows association rather than direction, both HOXA-AS2-to-partner and partner-to-HOXA-AS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HOXA-AS2 versus HOXA3_S184 in UCEC, with a Pearson correlation of 0.70.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXA-AS2→partner) and Y-score (partner→HOXA-AS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HOXA3_S184 →	+2.081	+1.324	<.001	<.001	3	7
OV	HOXA4_S109 →	+1.611	+1.851	<.001	<.001	3	5
GBM	HOXA3_S263 →	+0.793	+1.798	.007	.003	3	4
BRCA	SEPTIN2 →	+0.227	+0.467	<.001	<.001	3	4
COAD	SEPTIN8 →	+0.378	+0.829	<.001	<.001	3	4
OV	EFEMP1 →	+0.738	+1.008	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,085 associations by consensus.

HOXA-AS2 vs HOXA3_S184 — UCEC

Explore this scatter interactively →