HORMAD1

Across TCGA patient cohorts, HORMAD1 mutation is significantly associated with the RNA expression of many other genes, with 1,265 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HORMAD1-associated genes across cancer lineages are RNU6-709P, MIR6798, and RN7SL478P. Each is linked with HORMAD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both HORMAD1-to-partner and partner-to-HORMAD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-709P grouped by HORMAD1-low versus HORMAD1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HORMAD1→partner) and Y-score (partner→HORMAD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-709P →	+0.421	+4.821	<.001	.003	3	2
COAD	MIR6798 →	+0.360	+4.595	<.001	.004	3	2
UCEC	RN7SL478P →	+0.157	+1.617	.007	.008	3	2
SKCM	RN7SL861P →	+0.294	+2.429	<.001	.007	3	2
HNSC	RNU6-1244P →	+0.347	+7.954	<.001	.008	3	2
SKCM	AQP7P5 →	+0.125	+2.910	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,265 associations by consensus.

RNU6-709P by HORMAD1 expression — COAD

Explore this box plot interactively →