HOPX

Across TCGA patient cohorts, HOPX RNA expression is significantly associated with the protein abundance of many other proteins, with 21,237 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible HOPX-associated proteins across cancer lineages are ZYX, SORBS3, and C11orf96. Each is linked with HOPX in more than 7 cancer types. Because this analysis shows association rather than direction, both HOPX-to-partner and partner-to-HOPX results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HOPX versus ZYX in COAD, with a Pearson correlation of 0.60.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HOPX→partner) and Y-score (partner→HOPX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ZYX →	+0.438	+0.996	<.001	<.001	3	8
UCEC	SORBS3 →	+0.597	+0.732	<.001	.001	3	8
OV	C11orf96 →	+0.508	+1.077	<.001	<.001	3	7
UCEC	CAVIN1 →	+0.802	+0.590	<.001	.005	3	7
OV	CLEC3B →	+0.643	+1.121	<.001	<.001	3	7
UCEC	CNRIP1 →	+0.633	+0.714	.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,237 associations by consensus.

HOPX vs ZYX — COAD

Explore this scatter interactively →