HOMER3-AS1

Across TCGA patient cohorts, HOMER3-AS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,170 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HOMER3-AS1-associated GO terms across cancer lineages are Collagen metabolic process, Cell junction disassembly, and Positive regulation of syncytium formation by plasma membrane fusion. Each is linked with HOMER3-AS1 in more than 22 cancer types. Because this analysis shows association rather than direction, both HOMER3-AS1-to-partner and partner-to-HOMER3-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Collagen metabolic process grouped by HOMER3-AS1-low versus HOMER3-AS1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HOMER3-AS1→partner) and Y-score (partner→HOMER3-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Collagen metabolic process →	+0.062	+0.260	<.001	<.001	3	22
STAD	Cell junction disassembly →	+0.085	+0.282	<.001	<.001	3	22
STAD	Positive regulation of syncytium formation by plasma membrane fusion →	+0.058	+0.217	<.001	<.001	3	21
SARC	Complement receptor mediated signaling pathway →	+0.082	+0.585	<.001	<.001	3	21
PAAD	Negative regulation of interleukin-10 production →	+0.069	+0.269	<.001	<.001	3	21
CHOL	Regulation of macrophage fusion →	+0.147	+0.330	.001	.004	1	23

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,170 associations by consensus.

Collagen metabolic process by HOMER3-AS1 expression — STAD

Explore this box plot interactively →