HNRNPR

Across TCGA cell cohorts, HNRNPR mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible HNRNPR-associated genes across cancer lineages are IFNA14, KRT28, and DEFB134. Each is linked with HNRNPR in more than 1 cancer types. Because this analysis shows association rather than direction, both HNRNPR-to-partner and partner-to-HNRNPR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IFNA14 grouped by HNRNPR-low versus HNRNPR-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HNRNPR→partner) and Y-score (partner→HNRNPR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	IFNA14 →	+0.022	+5.196	<.001	.005	3	1
LUNG_NSCLC_LUAD	KRT28 →	+0.006	+4.544	<.001	.003	3	1
LUNG_NSCLC_LUAD	DEFB134 →	+0.049	+4.371	.009	.005	3	1
LUNG_NSCLC_LUAD	OR4C12 →	+0.017	+4.662	<.001	.005	3	1
LARGE_INTESTINE	TPD52L3 →	+0.044	+3.684	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

IFNA14 by HNRNPR expression — OVARY

Explore this box plot interactively →