HNMT

Across TCGA patient cohorts, HNMT RNA expression is significantly associated with the protein abundance of many other proteins, with 23,762 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HNMT-associated proteins across cancer lineages are HAAO, DAB2, and FERMT2. Each is linked with HNMT in more than 7 cancer types. Because this analysis shows association rather than direction, both HNMT-to-partner and partner-to-HNMT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HNMT versus HAAO in HNSC, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HNMT→partner) and Y-score (partner→HNMT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	HAAO →	+0.593	+0.976	<.001	<.001	3	8
HNSC	DAB2 →	+0.475	+0.793	<.001	<.001	3	7
COAD	FERMT2 →	+0.575	+0.517	<.001	.002	3	7
LSCC	ILK →	+0.444	+0.724	<.001	<.001	3	7
OV	TBC1D2B →	+0.409	+1.356	<.001	<.001	3	7
OV	TNS1 →	+0.659	+0.765	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,762 associations by consensus.

HNMT vs HAAO — HNSC

Explore this scatter interactively →