HMMR-AS1

Across TCGA patient cohorts, HMMR-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,634 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HMMR-AS1-associated proteins across cancer lineages are NPM1_S254, RBBP5_S497, and CCNB1. Each is linked with HMMR-AS1 in more than 7 cancer types. Because this analysis shows association rather than direction, both HMMR-AS1-to-partner and partner-to-HMMR-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HMMR-AS1 versus NPM1_S254 in LUAD, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HMMR-AS1→partner) and Y-score (partner→HMMR-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	NPM1_S254 →	+1.021	+0.233	<.001	<.001	3	8
LSCC	RBBP5_S497 →	+0.867	+0.314	<.001	<.001	3	7
GBM	CCNB1 →	+0.722	+0.380	.001	<.001	3	7
LSCC	TPX2 →	+0.702	+0.307	<.001	<.001	3	7
LUAD	NPM1_T199 →	+1.735	+0.232	<.001	<.001	3	7
LSCC	RFC1_T506 →	+0.920	+0.324	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,634 associations by consensus.

HMMR-AS1 vs NPM1_S254 — LUAD

Explore this scatter interactively →