HMGN1P8

Across TCGA patient cohorts, HMGN1P8 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,270 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HMGN1P8-associated proteins across cancer lineages are SDF2, DBR1, and PAK2. Each is linked with HMGN1P8 in more than 4 cancer types. Because this analysis shows association rather than direction, both HMGN1P8-to-partner and partner-to-HMGN1P8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HMGN1P8 versus SDF2 in LSCC, with a Pearson correlation of 0.53.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGN1P8→partner) and Y-score (partner→HMGN1P8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SDF2 →	+0.432	+0.655	<.001	<.001	3	5
LSCC	DBR1 →	+0.432	+0.724	<.001	<.001	3	4
LSCC	PAK2 →	+0.250	+0.534	.001	.008	3	4
LSCC	FXR1 →	+0.447	+0.804	<.001	<.001	3	4
LSCC	U2SURP →	+0.371	+0.782	<.001	<.001	3	3
LSCC	XAB2 →	+0.382	+0.721	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,270 associations by consensus.

HMGN1P8 vs SDF2 — LSCC

Explore this scatter interactively →