high mobility group nucleosome binding domain 1 pseudogene 8Genealiases: []
Q-omics provides the consensus-scored HMGN1P8 profile across patient tissues and cancer cell-line models. HMGN1P8 expression is associated with patient survival in 20 of 34 cancer types, with the highest sampling consensus in UVM. Among the 18 cancer types available for tumor–normal comparison, HMGN1P8 is differentially expressed in 11, with the highest sampling consensus in HNSC. Additionally, HMGN1P8 RNA expression shows 16,393 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight UVM, and HNSC as cancer lineages where HMGN1P8 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for HMGN1P8 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes HMGN1P8 survival associations across molecular data types. HMGN1P8 RNA expression shows survival associations in the most cancer types (20). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible HMGN1P8 RNA expression–survival associations across cancer types. High HMGN1P8 expression shows unfavorable associations in UVM, MESO, PAAD, THCA and BLCA, but favorable associations in UCEC. The UVM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .007). Together, the overview and detailed table identify UVM as the clearest survival context for HMGN1P8 RNA expression.
This table summarizes HMGN1P8 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 11. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for HMGN1P8. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. HMGN1P8 shows higher tumor expression in HNSC, BLCA, KIRC, LUSC, BRCA and STAD. The HNSC box plot shows higher HMGN1P8 RNA expression in tumor versus normal tissue (log2 FC = +0.358, t-test p < 0.001).
This table shows molecular features associated with HMGN1P8 in patient tissues and cancer cell lines. In patient samples, HMGN1P8 shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set.
