HMGB3P31

Across TCGA patient cohorts, HMGB3P31 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,066 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HMGB3P31-associated GO terms across cancer lineages are Transcription initiation at RNA polymerase I promoter, Nuclear export, and Golgi organization. Each is linked with HMGB3P31 in more than 13 cancer types. Because this analysis shows association rather than direction, both HMGB3P31-to-partner and partner-to-HMGB3P31 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transcription initiation at RNA polymerase I promoter grouped by HMGB3P31-low versus HMGB3P31-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB3P31→partner) and Y-score (partner→HMGB3P31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Transcription initiation at RNA polymerase I promoter →	+0.057	+0.167	<.001	<.001	3	14
STAD	Nuclear export →	+0.059	+0.111	<.001	<.001	3	13
STAD	Golgi organization →	+0.048	+0.095	<.001	<.001	3	13
STAD	Cytokinesis →	+0.050	+0.085	<.001	<.001	3	13
STAD	Internal protein amino acid acetylation →	+0.051	+0.122	<.001	<.001	3	13
ESCA	Protein modification by small protein removal →	+0.058	+0.200	.007	<.001	2	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,066 associations by consensus.

Transcription initiation at RNA polymerase I promoter by HMGB3P31 expression — ESCA

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