HMGB3P27

Across TCGA patient cohorts, HMGB3P27 RNA expression is significantly associated with the protein abundance of many other proteins, with 4,765 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible HMGB3P27-associated proteins across cancer lineages are AKAP12_S248, AKAP12_S651, and ZMYND8. Each is linked with HMGB3P27 in more than 2 cancer types. Because this analysis shows association rather than direction, both HMGB3P27-to-partner and partner-to-HMGB3P27 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HMGB3P27 versus AKAP12_S248 in OV, with a Pearson correlation of -0.28.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB3P27→partner) and Y-score (partner→HMGB3P27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	AKAP12_S248 →	-0.767	-0.282	.003	<.001	3	3
OV	AKAP12_S651 →	-1.059	-0.522	.001	.002	3	3
LSCC	ZMYND8 →	+0.244	+0.255	<.001	.005	3	2
HNSC	PRKN →	-0.895	-0.472	<.001	<.001	3	2
OV	ARHGEF40_S262 →	+0.787	+0.273	<.001	.003	3	2
COAD	UROS →	-0.281	-0.064	.008	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,765 associations by consensus.

HMGB3P27 vs AKAP12_S248 — OV

Explore this scatter interactively →