HMGB3P27

Across TCGA patient cohorts, HMGB3P27 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,448 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HMGB3P27-associated GO terms across cancer lineages are Positive regulation of post-translational protein modification, Transcription by RNA polymerase I, and Maturation of LSU-rRNA. Each is linked with HMGB3P27 in more than 11 cancer types. Because this analysis shows association rather than direction, both HMGB3P27-to-partner and partner-to-HMGB3P27 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of post-translational protein modification grouped by HMGB3P27-low versus HMGB3P27-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB3P27→partner) and Y-score (partner→HMGB3P27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of post-translational protein modification →	+0.050	+0.198	<.001	<.001	3	12
STAD	Transcription by RNA polymerase I →	+0.053	+0.237	<.001	<.001	3	12
STAD	Maturation of LSU-rRNA →	+0.049	+0.207	<.001	<.001	3	11
STAD	Ribosomal large subunit biogenesis →	+0.055	+0.213	<.001	<.001	3	11
STAD	Cerebral cortex development →	+0.032	+0.162	<.001	<.001	3	10
STAD	Mitochondrial translation →	+0.060	+0.220	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,448 associations by consensus.

Positive regulation of post-translational protein modification by HMGB3P27 expression — STAD

Explore this box plot interactively →