HMGB3P23

Across TCGA patient cohorts, HMGB3P23 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,851 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HMGB3P23-associated GO terms across cancer lineages are Exocytic process, Spliceosomal complex assembly, and Mitochondrial cytochrome c oxidase assembly. Each is linked with HMGB3P23 in more than 6 cancer types. Because this analysis shows association rather than direction, both HMGB3P23-to-partner and partner-to-HMGB3P23 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Exocytic process grouped by HMGB3P23-low versus HMGB3P23-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB3P23→partner) and Y-score (partner→HMGB3P23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Exocytic process →	+0.089	+0.048	<.001	<.001	3	7
STAD	Spliceosomal complex assembly →	+0.120	+0.056	<.001	<.001	3	7
STAD	Mitochondrial cytochrome c oxidase assembly →	+0.112	+0.046	<.001	<.001	3	7
STAD	Protein insertion into mitochondrial inner membrane →	+0.131	+0.051	<.001	<.001	3	7
STAD	Pyrimidine nucleotide biosynthetic process →	+0.104	+0.050	<.001	<.001	3	7
STAD	Receptor internalization →	+0.108	+0.050	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,851 associations by consensus.

Exocytic process by HMGB3P23 expression — STAD

Explore this box plot interactively →