HMGB3P16

Across TCGA patient cohorts, HMGB3P16 RNA expression is significantly associated with the protein abundance of many other proteins, with 3,966 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HMGB3P16-associated proteins across cancer lineages are TMF1_S344, SIPA1, and CARD11_S593. Each is linked with HMGB3P16 in more than 1 cancer types. Because this analysis shows association rather than direction, both HMGB3P16-to-partner and partner-to-HMGB3P16 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HMGB3P16 versus TMF1_S344 in LSCC, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB3P16→partner) and Y-score (partner→HMGB3P16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TMF1_S344 →	+0.370	+0.205	.001	.002	3	2
LSCC	SIPA1 →	+0.191	+0.130	.001	.005	3	2
LSCC	CARD11_S593 →	+0.439	+0.226	.004	<.001	3	2
LSCC	MORC2 →	-0.269	-0.241	<.001	<.001	3	2
LSCC	TRAPPC9 →	+0.119	+0.197	.001	.002	3	2
LSCC	TRMT10A →	-0.338	-0.166	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,966 associations by consensus.

HMGB3P16 vs TMF1_S344 — LSCC

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