HMGB3P12

Across TCGA patient cohorts, HMGB3P12 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,164 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HMGB3P12-associated GO terms across cancer lineages are Protein polyubiquitination, Telencephalon development, and Obsolete regulation of dosage compensation by inactivation of X chromosome. Each is linked with HMGB3P12 in more than 9 cancer types. Because this analysis shows association rather than direction, both HMGB3P12-to-partner and partner-to-HMGB3P12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein polyubiquitination grouped by HMGB3P12-low versus HMGB3P12-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB3P12→partner) and Y-score (partner→HMGB3P12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Protein polyubiquitination →	+0.102	+0.056	<.001	<.001	3	10
STAD	Telencephalon development →	+0.066	+0.060	<.001	<.001	3	10
STAD	Obsolete regulation of dosage compensation by inactivation of X chromosome →	+0.102	+0.050	<.001	<.001	3	9
STAD	Regulation of ERBB signaling pathway →	+0.094	+0.055	<.001	<.001	3	9
STAD	Positive regulation of proteasomal protein catabolic process →	+0.104	+0.059	<.001	<.001	3	9
STAD	Regulation of protein depolymerization →	+0.073	+0.056	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,164 associations by consensus.

Protein polyubiquitination by HMGB3P12 expression — STAD

Explore this box plot interactively →