HMGB1P9

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, HMGB1P9 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,900 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HMGB1P9-associated GO terms across cancer lineages are DNA conformation change, Cell cycle DNA replication, and Chromosome localization. Each is linked with HMGB1P9 in more than 18 cancer types. Because this analysis shows association rather than direction, both HMGB1P9-to-partner and partner-to-HMGB1P9 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB1P9→partner) and Y-score (partner→HMGB1P9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
ESCADNA conformation change →+0.071+0.233.005<.001219
ESCACell cycle DNA replication →+0.088+0.210<.001.001318
LAMLChromosome localization →+0.073+0.405<.001<.001317
DLBCsnRNA metabolic process →+0.063+0.212.003.004218
ESCAPositive regulation of mitotic cell cycle →+0.057+0.220<.001<.001317
ESCARegulation of cyclin-dependent protein kinase activity →+0.050+0.214.001<.001317
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,900 associations by consensus.

Exploration