HMGB1P5

Across TCGA patient cohorts, HMGB1P5 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,196 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HMGB1P5-associated proteins across cancer lineages are WDHD1, PBK, and CTDSPL2. Each is linked with HMGB1P5 in more than 5 cancer types. Because this analysis shows association rather than direction, both HMGB1P5-to-partner and partner-to-HMGB1P5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HMGB1P5 versus WDHD1 in LSCC, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB1P5→partner) and Y-score (partner→HMGB1P5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	WDHD1 →	+0.541	+0.594	.004	.001	3	6
LSCC	PBK →	+0.556	+0.665	<.001	<.001	3	6
GBM	CTDSPL2 →	+0.399	+0.588	.001	<.001	3	6
GBM	SMC2 →	+0.482	+0.480	.003	<.001	3	6
GBM	SMC4 →	+0.476	+0.472	.002	<.001	3	6
GBM	NCAPG →	+0.481	+0.519	.002	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,196 associations by consensus.

HMGB1P5 vs WDHD1 — LSCC

Explore this scatter interactively →