HMGB1P44

Across TCGA patient cohorts, HMGB1P44 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,524 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible HMGB1P44-associated GO terms across cancer lineages are Telomere maintenance via telomere lengthening, RNA modification, and Recombinational repair. Each is linked with HMGB1P44 in more than 19 cancer types. Because this analysis shows association rather than direction, both HMGB1P44-to-partner and partner-to-HMGB1P44 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Telomere maintenance via telomere lengthening grouped by HMGB1P44-low versus HMGB1P44-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB1P44→partner) and Y-score (partner→HMGB1P44) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Telomere maintenance via telomere lengthening →	+0.066	+0.120	<.001	<.001	3	20
ESCA	RNA modification →	+0.067	+0.248	<.001	<.001	3	20
ESCA	Recombinational repair →	+0.070	+0.286	<.001	<.001	3	19
STAD	mRNA transport →	+0.069	+0.117	<.001	<.001	3	18
STAD	Positive regulation of DNA metabolic process →	+0.063	+0.108	<.001	<.001	3	18
ESCA	Establishment of RNA localization →	+0.047	+0.178	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,524 associations by consensus.

Telomere maintenance via telomere lengthening by HMGB1P44 expression — STAD

Explore this box plot interactively →