Across TCGA patient cohorts, HMGB1P39 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,636 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HMGB1P39-associated proteins across cancer lineages are SYNPO2, C11orf96_S399, and FILIP1. Each is linked with HMGB1P39 in more than 4 cancer types. Because this analysis shows association rather than direction, both HMGB1P39-to-partner and partner-to-HMGB1P39 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB1P39→partner) and Y-score (partner→HMGB1P39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	SYNPO2 →	+0.633	+0.504	.001	.002	3	5
LSCC	C11orf96_S399 →	+0.747	+0.368	<.001	<.001	3	5
CCRCC	FILIP1 →	+0.647	+0.858	<.001	<.001	3	5
PDAC	SERPINF2 →	+0.452	+0.233	.001	.002	3	4
LSCC	GUCY1A2 →	+0.477	+0.530	<.001	<.001	3	4
HNSC	HRC_S333 →	+0.896	+0.589	.001	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,636 associations by consensus.

Exploration

HMGB1P39 survival (RNA) · tumor vs normal (RNA) · all HMGB1P39 data types