HMBOX1-IT1

Across TCGA patient cohorts, HMBOX1-IT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 5,330 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible HMBOX1-IT1-associated proteins across cancer lineages are CCAR2, RRAGC_T394, and PHF21A_T350. Each is linked with HMBOX1-IT1 in more than 4 cancer types. Because this analysis shows association rather than direction, both HMBOX1-IT1-to-partner and partner-to-HMBOX1-IT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HMBOX1-IT1 versus CCAR2 in UCEC, with a Pearson correlation of 0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HMBOX1-IT1→partner) and Y-score (partner→HMBOX1-IT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CCAR2 →	+0.218	+0.490	<.001	.006	3	5
CCRCC	RRAGC_T394 →	-0.820	-0.483	.001	.001	3	4
LSCC	PHF21A_T350 →	+0.751	+0.456	<.001	.002	3	3
PDAC	TUT7 →	-0.244	-0.373	<.001	<.001	3	3
HNSC	GBE1 →	+0.301	+0.828	<.001	.001	3	3
LSCC	LRCH4_S281 →	-0.425	-0.335	.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,330 associations by consensus.

HMBOX1-IT1 vs CCAR2 — UCEC

Explore this scatter interactively →