HLX-AS1

Across TCGA patient cohorts, HLX-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,852 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HLX-AS1-associated proteins across cancer lineages are COL14A1, FERMT2, and KANK2. Each is linked with HLX-AS1 in more than 4 cancer types. Because this analysis shows association rather than direction, both HLX-AS1-to-partner and partner-to-HLX-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HLX-AS1 versus COL14A1 in PDAC, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HLX-AS1→partner) and Y-score (partner→HLX-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	COL14A1 →	+0.674	+0.425	<.001	<.001	3	5
CCRCC	FERMT2 →	+0.371	+0.418	.001	.004	3	5
LUAD	KANK2 →	+0.475	+0.523	<.001	<.001	3	5
BRCA	MSRB3 →	+0.441	+0.271	.001	<.001	3	5
OV	PLAC9 →	+0.738	+0.297	.001	.002	3	5
CCRCC	PEAK1 →	+0.331	+0.487	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,852 associations by consensus.

HLX-AS1 vs COL14A1 — PDAC

Explore this scatter interactively →