HLA-T

Across TCGA patient cohorts, HLA-T RNA expression is significantly associated with the RNA expression of many other genes, with 14,630 significant associations in total. THYM shows the largest number of these associations.

The most reproducible HLA-T-associated genes across cancer lineages are BTN2A3P, BTN3A1, and BTN2A1. Each is linked with HLA-T in more than 28 cancer types. Because this analysis shows association rather than direction, both HLA-T-to-partner and partner-to-HLA-T results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HLA-T versus BTN2A3P in UVM, with a Pearson correlation of 0.50.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HLA-T→partner) and Y-score (partner→HLA-T) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UVM	BTN2A3P →	+0.905	+0.250	<.001	<.001	3	29
UVM	BTN3A1 →	+1.229	+0.162	<.001	<.001	3	28
UVM	BTN2A1 →	+1.047	+0.220	<.001	.001	3	28
LAML	DLSTP1 →	+0.522	+0.550	<.001	<.001	3	28
THYM	LRRC37A17P →	+0.777	+0.199	<.001	<.001	3	27
PCPG	DUSP8P5 →	+0.680	+0.218	<.001	<.001	3	27

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,630 associations by consensus.

HLA-T vs BTN2A3P — UVM

Explore this scatter interactively →