Q-omics provides the consensus-scored DLSTP1 profile across patient tissues and cancer cell-line models. DLSTP1 expression is associated with patient survival in 22 of 34 cancer types, with the highest sampling consensus in UCS. Among the 18 cancer types available for tumor–normal comparison, DLSTP1 is differentially expressed in 6, with the highest sampling consensus in BRCA. Additionally, DLSTP1 RNA expression shows 20,367 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight UCS, BRCA, and THYM as cancer lineages where DLSTP1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for DLSTP1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes DLSTP1 survival associations across molecular data types. DLSTP1 RNA expression shows survival associations in the most cancer types (22). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible DLSTP1 RNA expression–survival associations across cancer types. High DLSTP1 expression shows unfavorable associations in LGG and UCEC, but favorable associations in UCS, BRCA, PAAD and HNSC. The UCS Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .001). Together, the overview and detailed table identify UCS as the clearest survival context for DLSTP1 RNA expression.
This table summarizes DLSTP1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 6. The strongest signals are observed in BRCA for RNA.
This table ranks reproducible tumor–normal expression differences for DLSTP1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. DLSTP1 shows lower tumor expression in BRCA, THCA, KIRP and KICH and higher tumor expression in CHOL and LIHC. The BRCA box plot shows higher DLSTP1 RNA expression in normal versus tumor tissue (log2 FC = −0.406, t-test p < 0.001).
This table shows molecular features associated with DLSTP1 in patient tissues and cancer cell lines. In patient samples, DLSTP1 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set. In cancer cell lines, DLSTP1 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in UPPER_AERODIGESTIVE_TRACT, while CRISPR and shRNA rows add functional-dependency signals in SKIN.
