HLA-G

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, HLA-G protein abundance is significantly associated with the protein abundance of many other proteins, with 2,002 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible HLA-G-associated proteins across cancer lineages are STAT1, UBE2L6, and GBP1. Each is linked with HLA-G in more than 1 cancer types. Because this analysis shows association rather than direction, both HLA-G-to-partner and partner-to-HLA-G results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HLA-G→partner) and Y-score (partner→HLA-G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVSTAT1 →+0.723+1.065.002.00132
OVUBE2L6 →+0.759+1.054.001.00132
OVGBP1 →+1.085+1.281.001<.00132
LSCCDROSHA_S373 →-0.737-0.745<.001.00131
LSCCANK1_S1396 →+1.182+0.580<.001<.00131
OVSAMD9 →+1.234+1.301<.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,002 associations by consensus.

Exploration