Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts
Across TCGA patient cohorts, HLA-DRB5 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. SKCM shows the largest number of these associations.
The most reproducible HLA-DRB5-associated genes across cancer lineages are RNU6-709P and MIR206. Each is linked with HLA-DRB5 in more than 1 cancer types. Because this analysis shows association rather than direction, both HLA-DRB5-to-partner and partner-to-HLA-DRB5 results are reported.
Each partner links to its own Q-omics profile.
mutation associated genes by consensus
Ranked by combined sampling and lineage consensus. X-score (HLA-DRB5→partner) and Y-score (partner→HLA-DRB5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.