HLA-DQB1

Across TCGA patient cohorts, HLA-DQB1 mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. COAD shows the largest number of these associations.

The most reproducible HLA-DQB1-associated genes across cancer lineages are Fibroblasts. Each is linked with HLA-DQB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both HLA-DQB1-to-partner and partner-to-HLA-DQB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Fibroblasts grouped by HLA-DQB1-low versus HLA-DQB1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HLA-DQB1→partner) and Y-score (partner→HLA-DQB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Fibroblasts →	+0.025	+5.721	.044	.036	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Fibroblasts by HLA-DQB1 expression — COAD

Explore this box plot interactively →