HLA-DPA1

Across TCGA patient cohorts, HLA-DPA1 mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible HLA-DPA1-associated genes across cancer lineages are Neutrophils. Each is linked with HLA-DPA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both HLA-DPA1-to-partner and partner-to-HLA-DPA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Neutrophils grouped by HLA-DPA1-low versus HLA-DPA1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HLA-DPA1→partner) and Y-score (partner→HLA-DPA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Neutrophils →	+0.025	+2.615	<.001	.034	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Neutrophils by HLA-DPA1 expression — SKCM

Explore this box plot interactively →