HIP1R

Across TCGA patient cohorts, HIP1R protein abundance is significantly associated with the RNA expression of many other genes, with 15,153 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible HIP1R-associated genes across cancer lineages are RASAL1, SPRING1, and BICDL1. Each is linked with HIP1R in more than 6 cancer types. Because this analysis shows association rather than direction, both HIP1R-to-partner and partner-to-HIP1R results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HIP1R versus RASAL1 in HNSC, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HIP1R→partner) and Y-score (partner→HIP1R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RASAL1 →	+1.301	+0.663	<.001	<.001	3	7
PDAC	SPRING1 →	+0.513	+0.430	<.001	<.001	3	6
CCRCC	BICDL1 →	+0.993	+0.251	<.001	<.001	3	6
LUAD	PRKAB1 →	+0.797	+0.397	<.001	<.001	3	6
UCEC	BNC2 →	-1.611	-0.379	<.001	<.001	3	6
UCEC	ZNF664 →	+0.498	+0.331	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,153 associations by consensus.

HIP1R vs RASAL1 — HNSC

Explore this scatter interactively →