HIKESHIP3

Across TCGA patient cohorts, HIKESHIP3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,339 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HIKESHIP3-associated GO terms across cancer lineages are Positive regulation of translation, Vacuolar transport, and Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. Each is linked with HIKESHIP3 in more than 16 cancer types. Because this analysis shows association rather than direction, both HIKESHIP3-to-partner and partner-to-HIKESHIP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of translation grouped by HIKESHIP3-low versus HIKESHIP3-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HIKESHIP3→partner) and Y-score (partner→HIKESHIP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of translation →	+0.059	+0.267	<.001	<.001	3	17
STAD	Vacuolar transport →	+0.061	+0.265	<.001	<.001	3	17
STAD	Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.060	+0.264	<.001	<.001	3	17
STAD	Signal transduction by p53 class mediator →	+0.056	+0.266	<.001	<.001	3	16
STAD	Protein localization to vacuole →	+0.061	+0.269	<.001	<.001	3	16
STAD	Regulation of proteolysis involved in protein catabolic process →	+0.060	+0.304	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,339 associations by consensus.

Positive regulation of translation by HIKESHIP3 expression — STAD

Explore this box plot interactively →