HIKESHI

Across TCGA patient cohorts, HIKESHI RNA expression is significantly associated with the protein abundance of many other proteins, with 10,201 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HIKESHI-associated proteins across cancer lineages are FAM76B_S193, RNF214, and AASDHPPT. Each is linked with HIKESHI in more than 5 cancer types. Because this analysis shows association rather than direction, both HIKESHI-to-partner and partner-to-HIKESHI results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HIKESHI versus FAM76B_S193 in OV, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HIKESHI→partner) and Y-score (partner→HIKESHI) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	FAM76B_S193 →	+0.586	+0.480	.001	<.001	3	6
LSCC	RNF214 →	+0.261	+0.451	<.001	<.001	3	5
HNSC	AASDHPPT →	+0.366	+0.414	<.001	<.001	2	6
LUAD	APIP_S87 →	+0.549	+0.263	.002	.003	3	4
GBM	MRE11 →	+0.238	+0.207	<.001	<.001	3	4
GBM	MSH2 →	+0.372	+0.257	.007	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,201 associations by consensus.

HIKESHI vs FAM76B_S193 — OV

Explore this scatter interactively →