HIF1AP1

Across TCGA patient cohorts, HIF1AP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,943 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible HIF1AP1-associated GO terms across cancer lineages are Regulation of microtubule-based process, Glycerolipid biosynthetic process, and Nucleotide-excision repair. Each is linked with HIF1AP1 in more than 17 cancer types. Because this analysis shows association rather than direction, both HIF1AP1-to-partner and partner-to-HIF1AP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of microtubule-based process grouped by HIF1AP1-low versus HIF1AP1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HIF1AP1→partner) and Y-score (partner→HIF1AP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Regulation of microtubule-based process →	+0.040	+0.286	.002	.001	1	18
ESCA	Glycerolipid biosynthetic process →	+0.037	+0.317	.003	<.001	2	17
ESCA	Nucleotide-excision repair →	+0.044	+0.320	.001	<.001	2	17
THYM	Regulation of DNA repair →	+0.024	+0.191	<.001	<.001	3	16
THYM	Regulation of double-strand break repair →	+0.023	+0.221	<.001	<.001	3	15
DLBC	Regulation of mRNA catabolic process →	+0.050	+0.388	.001	<.001	2	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,943 associations by consensus.

Regulation of microtubule-based process by HIF1AP1 expression — ESCA

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