HIF1AN

Across TCGA cell cohorts, HIF1AN mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible HIF1AN-associated genes across cancer lineages are TBC1D3. Each is linked with HIF1AN in more than 1 cancer types. Because this analysis shows association rather than direction, both HIF1AN-to-partner and partner-to-HIF1AN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TBC1D3 grouped by HIF1AN-low versus HIF1AN-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HIF1AN→partner) and Y-score (partner→HIF1AN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TBC1D3 →	+0.091	+4.273	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

TBC1D3 by HIF1AN expression — LARGE_INTESTINE

Explore this box plot interactively →