HIF1A-AS3

Across TCGA patient cohorts, HIF1A-AS3 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,508 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible HIF1A-AS3-associated proteins across cancer lineages are P4HA1, PLOD2, and COL12A1. Each is linked with HIF1A-AS3 in more than 6 cancer types. Because this analysis shows association rather than direction, both HIF1A-AS3-to-partner and partner-to-HIF1A-AS3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HIF1A-AS3 versus P4HA1 in BRCA, with a Pearson correlation of 0.67.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HIF1A-AS3→partner) and Y-score (partner→HIF1A-AS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	P4HA1 →	+0.723	+1.075	<.001	<.001	3	7
LUAD	PLOD2 →	+0.831	+0.737	<.001	<.001	3	7
LSCC	COL12A1 →	+0.906	+0.697	<.001	<.001	3	7
COAD	GBE1 →	+0.397	+1.030	<.001	<.001	3	7
GBM	SLC16A3 →	+0.815	+0.652	<.001	<.001	3	6
PDAC	SLC16A3_S436 →	+1.036	+0.816	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,508 associations by consensus.

HIF1A-AS3 vs P4HA1 — BRCA

Explore this scatter interactively →