HIF1A-AS1

Across TCGA patient cohorts, HIF1A-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,961 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible HIF1A-AS1-associated proteins across cancer lineages are BICRAL_S675, CABLES1, and AHNAK2_S3408. Each is linked with HIF1A-AS1 in more than 2 cancer types. Because this analysis shows association rather than direction, both HIF1A-AS1-to-partner and partner-to-HIF1A-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HIF1A-AS1 versus BICRAL_S675 in BRCA, with a Pearson correlation of -0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HIF1A-AS1→partner) and Y-score (partner→HIF1A-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	BICRAL_S675 →	-0.337	-0.239	<.001	<.001	3	3
LUAD	CABLES1 →	-0.467	-0.413	<.001	<.001	3	3
LUAD	AHNAK2_S3408 →	+0.996	+0.362	.001	<.001	3	3
GBM	EGFR →	+1.147	+0.538	<.001	<.001	3	3
BRCA	EGFR_S1064 →	+1.579	+0.454	.003	.007	3	3
LUAD	ELF1 →	-0.175	-0.354	.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,961 associations by consensus.

HIF1A-AS1 vs BICRAL_S675 — BRCA

Explore this scatter interactively →