HERPUD2

Across TCGA patient cohorts, HERPUD2 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,878 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible HERPUD2-associated proteins across cancer lineages are SEPTIN8, NUDCD3, and PURB. Each is linked with HERPUD2 in more than 6 cancer types. Because this analysis shows association rather than direction, both HERPUD2-to-partner and partner-to-HERPUD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HERPUD2 versus SEPTIN8 in BRCA, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HERPUD2→partner) and Y-score (partner→HERPUD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SEPTIN8 →	+0.354	+0.456	<.001	<.001	3	7
BRCA	NUDCD3 →	+0.314	+0.423	<.001	<.001	3	6
HNSC	PURB →	+0.439	+0.505	<.001	.001	3	6
LSCC	GMPPB →	-0.264	-0.314	.003	<.001	3	6
LSCC	SUN1 →	+0.333	+0.379	<.001	<.001	3	5
LSCC	CDK13 →	+0.236	+0.420	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,878 associations by consensus.

HERPUD2 vs SEPTIN8 — BRCA

Explore this scatter interactively →