HERPUD2

Across TCGA patient cohorts, HERPUD2 mutation is significantly associated with the RNA expression of many other genes, with 2,930 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HERPUD2-associated genes across cancer lineages are OR6M2P, RPS12P24, and RNU6-718P. Each is linked with HERPUD2 in more than 2 cancer types. Because this analysis shows association rather than direction, both HERPUD2-to-partner and partner-to-HERPUD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR6M2P grouped by HERPUD2-low versus HERPUD2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HERPUD2→partner) and Y-score (partner→HERPUD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	OR6M2P →	+0.354	+6.122	<.001	.002	3	3
CESC	RPS12P24 →	+0.102	+5.418	<.001	.005	3	2
UCEC	RNU6-718P →	+0.112	+3.069	.002	.005	3	2
UCEC	RNA5SP291 →	+0.093	+4.019	<.001	.005	3	2
UCEC	NAMPTP3 →	+0.194	+1.694	<.001	.008	3	2
UCEC	SNORD3B-2 →	+0.703	+1.936	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,930 associations by consensus.

OR6M2P by HERPUD2 expression — COAD

Explore this box plot interactively →