HEMK1

Across TCGA patient cohorts, HEMK1 protein abundance is significantly associated with the RNA expression of many other genes, with 2,701 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible HEMK1-associated genes across cancer lineages are CRIPT, MICALL1, and AMMECR1. Each is linked with HEMK1 in more than 2 cancer types. Because this analysis shows association rather than direction, both HEMK1-to-partner and partner-to-HEMK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HEMK1 versus CRIPT in CCRCC, with a Pearson correlation of -0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HEMK1→partner) and Y-score (partner→HEMK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	CRIPT →	-0.439	-0.609	.004	.008	3	3
BRCA	MICALL1 →	-0.771	-0.446	.001	.003	3	2
BRCA	AMMECR1 →	-0.767	-0.358	<.001	.005	3	2
BRCA	ATP11C →	-0.510	-0.350	.005	.002	3	2
BRCA	OIP5 →	-0.667	-0.419	<.001	.001	3	2
BRCA	STX2 →	-0.544	-0.439	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,701 associations by consensus.

HEMK1 vs CRIPT — CCRCC

Explore this scatter interactively →