HEMK1

Across TCGA cell cohorts, HEMK1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,476 significant associations in total. CNS shows the largest number of these associations.

The most reproducible HEMK1-associated GO terms across cancer lineages are GDP-mannose biosynthetic process, Flagellated sperm motility, and Sperm motility. Each is linked with HEMK1 in more than 11 cancer types. Because this analysis shows association rather than direction, both HEMK1-to-partner and partner-to-HEMK1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GDP-mannose biosynthetic process grouped by HEMK1-low versus HEMK1-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HEMK1→partner) and Y-score (partner→HEMK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	GDP-mannose biosynthetic process →	+0.201	+1.457	<.001	.001	3	12
UPPER_AERODIGESTIVE_TRACT	Flagellated sperm motility →	-0.109	-0.871	.002	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Sperm motility →	-0.109	-0.871	.002	<.001	3	10
URINARY_TRACT	Positive regulation of pinocytosis →	+0.110	+0.936	.001	.001	3	9
BREAST	GDP-mannose metabolic process →	+0.122	+1.115	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Glycerophospholipid metabolic process →	+0.038	+0.866	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,476 associations by consensus.

GDP-mannose biosynthetic process by HEMK1 expression — URINARY_TRACT

Explore this box plot interactively →