HEMK1

Across TCGA cell cohorts, HEMK1 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible HEMK1-associated genes across cancer lineages are DMRTB1. Each is linked with HEMK1 in more than 1 cancer types. Because this analysis shows association rather than direction, both HEMK1-to-partner and partner-to-HEMK1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DMRTB1 grouped by HEMK1-low versus HEMK1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HEMK1→partner) and Y-score (partner→HEMK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	DMRTB1 →	+0.006	+4.887	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

DMRTB1 by HEMK1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →