HEBP2

Across TCGA patient cohorts, HEBP2 protein abundance is significantly associated with the RNA expression of many other genes, with 7,048 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible HEBP2-associated genes across cancer lineages are SERINC1, CAB39L, and SESN1. Each is linked with HEBP2 in more than 6 cancer types. Because this analysis shows association rather than direction, both HEBP2-to-partner and partner-to-HEBP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HEBP2 versus SERINC1 in BRCA, with a Pearson correlation of 0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HEBP2→partner) and Y-score (partner→HEBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SERINC1 →	+0.619	+0.462	<.001	<.001	3	7
LSCC	CAB39L →	+0.714	+0.294	<.001	<.001	3	6
BRCA	SESN1 →	+0.858	+0.417	<.001	<.001	3	6
LSCC	MED23 →	+0.508	+0.263	<.001	<.001	3	6
GBM	STX7 →	+0.416	+0.344	<.001	<.001	3	6
BRCA	PERP →	+0.933	+0.534	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,048 associations by consensus.

HEBP2 vs SERINC1 — BRCA

Explore this scatter interactively →