HEBP1

Across TCGA patient cohorts, HEBP1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,575 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HEBP1-associated genes across cancer lineages are HTR7P1, CDC20, and ORC1. Each is linked with HEBP1 in more than 6 cancer types. Because this analysis shows association rather than direction, both HEBP1-to-partner and partner-to-HEBP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HEBP1 versus HTR7P1 in BRCA, with a Pearson correlation of 0.77.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HEBP1→partner) and Y-score (partner→HEBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	HTR7P1 →	+1.204	+0.799	<.001	<.001	3	7
BRCA	CDC20 →	-1.066	-0.594	<.001	<.001	3	6
OV	ORC1 →	-0.936	-0.439	<.001	.006	3	6
GBM	CLSPN →	-0.723	-0.349	<.001	<.001	3	6
OV	E2F8 →	-1.349	-0.587	<.001	.004	3	5
OV	SUV39H1 →	-0.609	-0.457	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,575 associations by consensus.

HEBP1 vs HTR7P1 — BRCA

Explore this scatter interactively →