HEBP1

Across TCGA pan-cancer cohorts, HEBP1 RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated HEBP1 data layer compared with 5 for mutation status and 5 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher HEBP1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated HEBP1 expression acts as an unfavorable survival marker, although some lineages such as DLBC and ACC show a favorable association.

UCEC, PAAD, and DLBC are the cancer types where HEBP1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	All	0.898	0.954	.005	60	view →
PAAD	OS	Median	All	0.253	0.516	<.001	50	view →
DLBC	OS	Median	All	1.000	0.359	<.001	46	view →
LGG	DFS	Median	All	0.657	0.814	<.001	45	view →
HNSC	OS	Median	All	0.709	0.789	.003	45	view →
ACC	DFS	Quartile	III,IV	0.694	0.065	.001	45	view →
GBM	DFS	Quartile	All	0.214	0.502	.005	27	view →
COAD	DFS	Median	IV	0.332	0.616	<.001	27	view →
UCS	OS	Tertile	IV	0.241	0.844	.024	24	view →
KIRP	DFS	Median	IV	0.036	0.528	.001	18	view →
SKCM	DFS	Median	III,IV	0.700	0.521	.003	16	view →
KIRC	DFS	Quartile	IV	0.279	0.608	.018	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

HEBP1–UCEC (OS)

Open the UCEC breakdown →