HEBP1

Across TCGA cell cohorts, HEBP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,810 significant associations in total. BONE shows the largest number of these associations.

The most reproducible HEBP1-associated GO terms across cancer lineages are Positive regulation of focal adhesion assembly, Maintenance of protein localization in organelle, and Positive regulation of cell-substrate junction organization. Each is linked with HEBP1 in more than 7 cancer types. Because this analysis shows association rather than direction, both HEBP1-to-partner and partner-to-HEBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of focal adhesion assembly grouped by HEBP1-low versus HEBP1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HEBP1→partner) and Y-score (partner→HEBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of focal adhesion assembly →	+0.251	+0.779	<.001	.002	3	8
BONE	Maintenance of protein localization in organelle →	+0.157	+1.333	<.001	.009	3	8
BONE	Positive regulation of cell-substrate junction organization →	+0.158	+0.709	<.001	.004	3	7
LARGE_INTESTINE	Chaperone-mediated autophagy →	+0.145	+0.728	<.001	<.001	2	8
LUNG_SCLC	Receptor-mediated endocytosis →	+0.040	+1.174	.003	.002	3	7
BONE	Positive regulation of protein exit from endoplasmic reticulum →	+0.160	+0.929	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,810 associations by consensus.

Positive regulation of focal adhesion assembly by HEBP1 expression — BONE

Explore this box plot interactively →