HEATR6

Across TCGA patient cohorts, HEATR6 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,182 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HEATR6-associated proteins across cancer lineages are SUPT16H, COIL, and EIF4A3. Each is linked with HEATR6 in more than 5 cancer types. Because this analysis shows association rather than direction, both HEATR6-to-partner and partner-to-HEATR6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HEATR6 versus SUPT16H in LSCC, with a Pearson correlation of 0.52.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HEATR6→partner) and Y-score (partner→HEATR6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SUPT16H →	+0.338	+0.378	<.001	<.001	3	6
LSCC	COIL →	+0.542	+0.599	<.001	<.001	3	6
LSCC	EIF4A3 →	+0.276	+0.535	<.001	<.001	3	6
GBM	HNRNPLL →	+0.257	+0.247	<.001	<.001	3	6
LSCC	TBL1XR1 →	+0.508	+0.567	<.001	<.001	3	5
LSCC	THOC5 →	+0.296	+0.520	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,182 associations by consensus.

HEATR6 vs SUPT16H — LSCC

Explore this scatter interactively →