HCRT

Across TCGA cell cohorts, HCRT RNA expression is significantly associated with the RNA expression of many other genes, with 1,174 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible HCRT-associated genes across cancer lineages are KRTAP5-5, ECE2, and LEUTX. Each is linked with HCRT in more than 2 cancer types. Because this analysis shows association rather than direction, both HCRT-to-partner and partner-to-HCRT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HCRT versus KRTAP5-5 in LUNG_NSCLC_LUSC, with a Pearson correlation of 0.58.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HCRT→partner) and Y-score (partner→HCRT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	KRTAP5-5 →	+0.229	+0.095	<.001	.002	3	3
STOMACH	ECE2 →	+0.718	+0.050	.002	.003	3	3
BONE	LEUTX →	+0.122	+0.194	.006	<.001	3	2
LUNG_NSCLC_LUSC	ADIG →	+0.038	+0.152	<.001	<.001	3	2
LUNG_NSCLC_LUSC	OR1G1 →	+0.130	+0.095	<.001	.002	3	2
LUNG_SCLC	OR51J1 →	+0.064	+0.514	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,174 associations by consensus.

HCRT vs KRTAP5-5 — LUNG_NSCLC_LUSC

Explore this scatter interactively →