Across TCGA patient cohorts, HCG9 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HCG9-associated genes across cancer lineages are MIR5691, ATP5MGP6, and RN7SL248P. Each is linked with HCG9 in more than 1 cancer types. Because this analysis shows association rather than direction, both HCG9-to-partner and partner-to-HCG9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HCG9→partner) and Y-score (partner→HCG9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR5691 →	+0.997	+4.694	<.001	.007	3	1
UCEC	ATP5MGP6 →	+0.823	+5.003	<.001	.002	3	1
UCEC	RN7SL248P →	+0.222	+5.722	<.001	.001	3	1
UCEC	TRBV17 →	+0.473	+4.256	<.001	.008	3	1
UCEC	RNU1-17P →	+0.723	+5.520	<.001	<.001	3	1
UCEC	RNU6-628P →	+1.116	+4.473	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Exploration

HCG9 survival (RNA) · tumor vs normal (RNA) · all HCG9 data types