HCFC1R1

Across TCGA patient cohorts, HCFC1R1 mutation is significantly associated with the RNA expression of many other genes, with 20 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HCFC1R1-associated genes across cancer lineages are LINC01519, NFYAP1, and RNA5SP73. Each is linked with HCFC1R1 in more than 1 cancer types. Because this analysis shows association rather than direction, both HCFC1R1-to-partner and partner-to-HCFC1R1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01519 grouped by HCFC1R1-low versus HCFC1R1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HCFC1R1→partner) and Y-score (partner→HCFC1R1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	LINC01519 →	+0.028	+5.669	<.001	.003	3	1
CESC	NFYAP1 →	+0.236	+5.010	<.001	.009	3	1
CESC	RNA5SP73 →	+0.611	+6.837	<.001	<.001	3	1
CESC	IGHVIV-44-1 →	+0.218	+5.201	<.001	.007	3	1
CESC	CYCSP22 →	+0.160	+6.569	<.001	.001	3	1
CESC	FAM47A →	+0.048	+5.306	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

LINC01519 by HCFC1R1 expression — CESC

Explore this box plot interactively →